Medical cannabis reduces nausea and vomiting caused by chemotherapy


Preliminary results and first global trial: significant improvement in nausea and vomiting due to chemotherapy

Researchers from the University of Sydney, Chris O’Brien Lifehouse and the NHMRC Center for Clinical Trials (The National Health and Medical Research Council : Australia’s leading funding body for medical research) have published preliminary results of a groundbreaking clinical trial of medicinal cannabis for cancer patients, which found that it can help reduce nausea and vomiting, two common and debilitating side effects of chemotherapy.

Preliminary results from a government-funded, University of Sydney, medical cannabis trial from New South Wales show significant improvement in nausea and vomiting from chemotherapy.

The CannabisCINV study, funded by $ 21 million invested by the Government of New South Wales to explore the therapeutic potential of medical cannabis, includes groundbreaking clinical trials around the world. The largest medical cannabis trial in the world at the time of its launch is a collaboration with leading cancer centers in New South Wales.

read : Cannabis for treating liver cancer

Results published in the Annals of Oncology revealed a significant improvement in the control of chemotherapy-induced nausea and vomiting. A quarter of patients taking medical cannabis experienced no vomiting or nausea, compared to 14% of people taking a placebo.

These encouraging results indicate that medical cannabis can help improve the quality of life of patients undergoing chemotherapy.

nausea, chemotherapy
Former New South Wales Prime Minister Mike Baird, Deputy Health Minister Pru ​​Goward and Associate Professor Peter Grimison

The pilot phase of the study lasted two and a half years, with 81 enrolled participants. To be included in the study, patients had to have previously suffered nausea and vomiting during chemotherapy despite taking medications to prevent nausea.

“Nausea and vomiting are among the most distressing and dreaded consequences of chemotherapy,” said lead researcher Peter Grimison, associate professor at the University of Sydney School of Medicine and Chris O’Brien Lifehouse medical oncologist.

These encouraging results indicate that medical cannabis can help improve the quality of life of patients undergoing chemotherapy.

read : New Research Confirms Cannabis Affects Brain Cancer, NOT the Brain

Side effects such as sedation, dizziness and drowsiness have been rated moderate to severe in about a third of people using medical cannabis, but are considered manageable.

“The trial will now move into a larger phase to determine with much more certainty the efficacy of medical cannabis and whether its use in routine cancer care should be considered,” said Professor Grimison from the School of Medicine and Health.

The next phase of the trial is underway and will recruit 170 more people.

The trial is sponsored by the University of Sydney. Medical cannabis is supplied by Tilray, a GMP certified medical cannabis producer.

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